TABLE 1

Pretherapeutic Parameters in Both Groups

ParameterGroup 1Group 2P
Total no. of patients3132Nonsignificant
Median age (y)7473Nonsignificant
Gleason score≤7 (30%)≤7 (41%)Nonsignificant
>7 (70%)>7 (59%)
No. of cyclesNonsignificant
 22 pts2 pts
 33 pts4 pts
 48 pts6 pts
 53 pts3 pts
 615 pts17 pts
Therapy
 Abirateronehistory of: 5 (16%); ongoing: 12 (38.7%)history of: 9 (28%); ongoing: 7 (21%)Nonsignificant
 Enzalutamidehistory of: 1 (3%); ongoing: 6 (19.3%)history of: 3 (9%); ongoing: 10 (31%)Nonsignificant
 History of chemotherapy16 (51.6%)11 (34%)Nonsignificant
Extent of bone metastases
 <64 pts (12.9%)5 pts (15.6%)Nonsignificant
 6–2010 pts (32.3%)12 pts (37.5%)
 >2017 pts (54.8%)15 pts (46.9%)
ECOG
 020 pts23 ptsNonsignificant
 19 pts8 pts
 22 pts1 pts
Mean labor value ± SD
 Hemoglobin (g/dL)12.2 ± 1.612.2 ± 1.4Nonsignificant
 White blood cell (G/L)6.8 ± 2.36.3 ± 1.6Nonsignificant
 Platelet (G/L)254 ± 110227 ± 54Nonsignificant
 PSA (ng/mL)153.10 ± 162.283.80 ± 116.6Nonsignificant
 ALP (U/L)185.3 ± 152.8169.8 ± 145.4Nonsignificant
 High ALP (>117U/L)19 pts18 ptsNonsignificant
  • pts = patients; ECOG = Eastern Cooperative Oncology Group performance status.