Target Volumes and Volumes of Organs at Risk in Experimental Arm Before and After 18F-Fluciclovine PET Registration
| Parameter | CTV | PTV | CTV1 | PTV1 | CTV2 | PTV2 |
| Target volume (cm3) | ||||||
| Preregistration | 137.7 ± 49.0 | 334.5 ± 79.4 | 472.8 ± 127.0 | 1114.8 ± 230.8 | 129.4 ± 42.9 | 320.8 ± 77.8 |
| Postregistration | 139.6 ± 49.6 | 339.2 ± 81.4 | 487.2 ± 132.6 | 1147.2 ± 237.9 | 131.4 ± 42.4 | 324.6 ± 75.5 |
| P | 0.034 | 0.009 | 0.007 | 0.002 | 0.027 | 0.147 |
| Dice similarity index | 0.99467 ± 0.01164 | 0.99279 ± 0.01099 | 0.98402 ± 0.03041 | 0.98673 ± 0.01588 | 0.99735 ± 0.02878 | 0.98118 ± 0.03793 |
| Maximum surface distance (mm) | 6.02 (0–17.99) | 5.94 (0–17.27) | 16.51 (0–31.33) | 14.33 (0–29.23) | 7.25 (0–34.44) | 6.99 (0–34.26) |
| Vector centroid | ||||||
| Mean difference (x, y, z) | 0.00, 0.00, 1.56 | 0.02, −0.05, 2.50 | −0.48, 0.22, 0.43 | −0.48, 0.35, 0.99 | 0.25, 0.44, −1.04 | −0.25, 0.19, 0.69 |
| Overall magnitude (mm) | 3.69 | 3.71 | 2.84 | 2.90 | 2.73 | 2.74 |
| Organs-at-risk volume (cm3) | ||||||
| Organ | Rectum, V40 | Rectum, V65 | Bladder, V40 | Bladder, V65 | Penile bulb, V40 | Penile bulb, V65 |
| Preregistration | 45.8 ± 10.2 | 17.8 ± 8.1 | 61.7 ± 19.5 | 33.3 ± 16.0 | 44.9 ± 30.4 | 21.6 ± 24.1 |
| Postregistration | 45.9 ± 11.9 | 18.1 ± 8.1 | 61.7 ± 18.9 | 33.8 ± 16.8 | 55.9 ± 34.4 | 32.6 ± 30.4 |
| P | 0.774 | 0.548 | 0.940 | 0.238 | 0.001 | 0.002 |
V40 = volume receiving 40 Gy; V65 = volume receiving 65 Gy.
Number of patients is 46. All P values were obtained using 2-tailed paired t test. Data in parentheses are range.