TABLE 1

Characteristics of RM Dosimetry Patients

Patient no.SexAge (y)Dose (MBq/kg)Injected activity (MBq)Pretreatment/predosing*Baseline thrombocytes (109/L)Baseline neutrophils (109/L)Prior treatment
1F58101,102R3454.5R×4; R-CHOP×2 plus CHOP×4
13M72151,416R1982.1R-CVP×6; R-bendamustin×6
14F70151,013R2432.8EBRT, 30 Gy; R×4; R-bendamustin×6; R-CHOP×6
15M68101,130R2063.6R-CHOP×6
2M58101,036R + lilotomab2332.6R×8; R×4; chlorambucil×6; R-CHOP×6; EBRT, 30 Gy; R-bendamustin×6; R×2
3M5010746R + lilotomab3397Chlorambucil×3; EBRT, 30 Gy; R-galiximab×6; R-CHOP×6; R maintenance
9M65151,696R + lilotomab2986.8R×4
12F49151,015R + lilotomab2683.1Intratumoral R with dendritic cells×3 plus EBRT, 8 Gy; intratumoral R with dendritic cells×2 plus EBRT, 8 Gy; R×4; R-bendamustin×1
  • * R refers to pretreatment with rituximab; lilotomab refers to predosing with unlabeled antibody.

  • R = rituximab; CHOP = cyclophosphamide, doxorubicin, vincristine, and prednisone; CVP = cyclophosphamide, vincristine and prednisone; EBRT = external-beam radiotherapy.