Metabolic and IWG Response for PFS, DOR, and OS
| Metabolic response | IWG best overall response | ||||
| Variable | CMR (n = 24) | Non-CMR (n = 8) | CR + PR (n = 29) | CR (n = 18) | Stable disease, progressive disease, or relapsed disease (n = 3) |
| PFS | |||||
| Median (95% CI) (mo) | 23.8 (17.2–41.5) | 10.7 (5.4–11.8) | 22.1 (16.2–38.4) | 38.4 (16.4–42.9) | 5.4 (2.4–11.8) |
| Kaplan–Meier estimate at 12 mo (no. at risk) | 91.48 (21) | 12.50 (1) | 78.57 (22) | 100.00 (17) | 0.00 (0) |
| DOR | |||||
| Median (95% CI) (mo) | 20.6 (14.6–38.8) | 7.8 (4.9–14.3) | 17.0 (13.3–35.5) | 35.5 (13.8–40.3) | NA |
| Kaplan–Meier estimate at 12 mo (no. at risk) | 86.36 (18) | 16.67 (1) | 71.43 (19) | 88.24 (15) | NA |
| OS | |||||
| Median (95% CI) (mo) | NR (32.1–NR) | 14.2 (8.6–18.8) | NR (28.9–NR) | NR (32.1–NR) | 16.1 (8.6–NR) |
| Kaplan–Meier estimate at 12 mo (no. at risk) | 100.00 (23) | 50.00 (4) | 89.29 (25) | 100.00 (17) | 66.67 (2) |
CI = confidence interval; NA = not applicable; NR = not reached.