TABLE 2

PDX Phenotype

Group	Latency^* (d)	SGR^*	CD133+	CD133+ CXCR4+ EpCAM⁻^†	KRAS (G12C)	LKB1	SUV_max^*
LT128	34.3 ± 5.4	0.06 ± 0.02	1.5%	4.8%	mut	(c.920 + 2T > A)	2.84 ± 0.41
LT187	29.3 ± 3.1	0.05 ± 0.01	0.2%	6%	wt	wt	0.97 ± 0.44
LT66	11.6 ± 1.3	0.13 ± 0.02	0.5%	ND	mut	c.298C > T	0.81 ± 0.15
LT59	38.8 ± 3.1	0.07 ± 0.02	85%	0.8%	wt	wt	0.74 ± 0.19
LT111	17.8 ± 2.0	0.09 ± 0.01	15%	2%	wt	wt	0.73 ± 0.14
LT73	18.3 ± 2.6	0.08 ± 0.03	3%	0.5%	wt	c.859A > T	0.37 ± 0.08
LT138	61.7 ± 8.1	0.07 ± 0.00	85%	0.3%	ND	c.354delC	1.16 ± 0.16
LT215	25.8 ± 7.4	0.10 ± 0.01	0.2%	4%	ND	wt	1.30 ± 0.33
LT120	25.0 ± 6.2	0.13 ± 0.02	30%	95%	ND	ND	1.34 ± 0.15

↵* Mean ± SD (n = 3/6 animals per group).
↵† Within CD133+ cells.
SGR = specific growth rate; mut = mutation; wt = wild type; ND = not determined.