TABLE 1

Task-Specific Changes in Glucose Metabolism for Eyes-Open Condition and Right-Finger Tapping as Compared with Baseline

Region	x (mm)	y (mm)	z (mm)	t value	CMRGlu baseline (μmol/100 g/min)	CMRGlu task (μmol/100 g/min)	Signal change (%)
Eyes open > baseline
Lingual L	−4	−88	−14	10.4^*	30.5 ± 5.4	1.1 ± 0.5	3.6 ± 1.4
Intracalcarine L	−8	−84	8	10.0^*	30.6 ± 5.2	0.9 ± 0.4	3.0 ± 1.1
Supracalcarine R	16	−66	14	10.4^*	33.8 ± 5.8	0.7 ± 0.3	2.2 ± 0.8
Occipital pole R	8	−96	−8	9.8^*	28.2 ± 6.3	1.1 ± 0.5	4.0 ± 1.9
Cuneus	0	−82	26	11.8^*	32.9 ± 5.3	0.8 ± 0.3	2.3 ± 0.8
Cerebellum crus II L	−12	−88	−24	17.2^*	24.8 ± 4.1	1.5 ± 0.5	6.1 ± 1.7
Cerebellum crus II R	8	−80	−28	9.4^*	26.1 ± 4.4	1.5 ± 0.7	5.5 ± 2.2
Cerebellum VI L	−28	−54	−28	16.5^*	26.8 ± 3.9	0.8 ± 0.2	3.1 ± 0.8
Cerebellum crus I L	−26	−88	−30	11.9^*	18.7 ± 3.5	0.8 ± 0.3	4.0 ± 1.5
Cerebellum crus I R	52	−52	−34	12.9^*	18.3 ± 3.5	1.1 ± 0.4	5.8 ± 1.8
Cerebellum vermis IX L	−2	−54	−30	11.8^*	20.4 ± 2.8	0.9 ± 0.3	4.2 ± 1.5
Hippocampus L	−30	−18	−12	9.7^*	19.4 ± 2.9	1.0 ± 0.4	5.2 ± 2.2
Eyes open < baseline
Frontal superior L	−18	32	46	−9.2^*	33.2 ± 6.7	−0.7 ± 0.4	−1.9 ± 0.8
Central L	−40	−24	58	−0.7	32.9 ± 5.3	−0.2 ± 0.8	−0.4 ± 2.2
Finger tapping > baseline
Central L	−40	−24	58	11.5^*	32.9 ± 5.3	2.1 ± 1.0	6.3 ± 2.8
Precentral L	−32	−16	70	10.7^*	22.7 ± 4.4	1.3 ± 0.6	5.7 ± 2.5
Hippocampus L	−28	−16	−12	12.1^*	19.4 ± 3.1	1.1 ± 0.4	5.6 ± 1.9
Cerebellum VI L	−32	−56	−26	13.0^*	29.6 ± 4.3	1.3 ± 0.4	4.3 ± 1.3
Cerebellum VI R	8	−64	−10	11.3^*	26.0 ± 3.6	0.9 ± 0.4	3.5 ± 1.3
Cerebellum crus I R	52	−52	−32	9.4^*	19.7 ± 4.0	1.0 ± 0.5	5.0 ± 2.2
Finger tapping < baseline
Intracalcarine L	−8	−84	8	−0.8	30.6 ± 5.2	−0.2 ± 0.7	−0.3 ± 2.3

↵* P < 0.05, FWE-corrected voxel level.
Significance thresholds were t = 8.7 for P < 0.05, FWE-corrected, and t = 3.8 for P < 0.001, uncorrected. Coordinates and t values were obtained from SPM analysis. Corresponding CMRGlu as obtained from Patlak plot is shown for baseline condition and each task as well as percentage signal changes from baseline.