TABLE 1

Demographics, Neurology, HTLV-1 Virology, and Immunology

Subject no. in analysis	Age (y)	Sex	Ethnicity	Duration disease (y)	Mobility aid	10-m TW (s)	PET	MRI	DWI	HTLV-1^* proviral load	CD8 DR	Disease
#1 HAMs1	55	Female	Caucasian	19	Frame	366	55 min	✓	✓	4.9	59	Severe HAM progressing
#2 HAMs2	48	Female	Caucasian	5	Frame	109	✓	✓	✓	17.4	47	Severe HAM progressing
#3 HAMmo	66	Female	Afro-Caribbean	8	1 stick	14.5	0 min	✓	x	3.8	42	Moderate HAM stable
#4 HAMmi	59	Female	Afro-Caribbean	2	Unaided	11.5	✓	✓	✓	7.9	32	Mild HAM stable
#5 HAMmo	54	Male	Afro-Caribbean	13	Elbow crutches	24.7	✓	✓	✓	10.5	32	Moderate HAM slow progression
#6 Asym1	57	Female	Afro-Caribbean	N/A	Unaided	6.5	✓	✓	✓	6.4	27	Asymptomatic
#7 Asym2	57	Male	Afro-Caribbean	N/A	Unaided	6.6	✓	✓	✓	2.6	17	Asymptomatic

↵* HTLV-1 DNA copies per 100 PBMCs.
10-m TW = time taken to walk 10 m on the flat; CD8 DR = % CD8 lymphocytes expressing human leukocyte antigen–antigen D related; HAMs1 = patient 1, severe HAM; HAMs2 = patient 2, severe HAM; HAMmo = patient 5, moderate HAM; HAMmi = patient 4, mild HAM; Asym1 = patient 6, asymptomatic; Asym 2 = patient 7, asymptomatic.