Binding Affinity of WAY-100635 Analogs vs. 11C-CUMI-101 to α1-Adrenoceptors in Human Cerebellum
| Compound | Ki (nM) | SD (n = 3) |
| Prazosin | 0.27 | 0.02 |
| CUMI-101 | 2.80 | 0.50 |
| WAY-100635 | 120.68 | 35.15 |
| DWAY | 78.96 | 29.33 |
| FCWAY | 87.11 | 22.85 |
| MefWAY (trans) | 116.60 | 15.70 |
For prazosin, value is KD (dissociation constant) instead of Ki.