WB and Serum Kinetic Parameters
| Parameter | 10 mg | 20 mg | 50 mg | Overall mean ± SD |
| WB biologic half-life (h) | 143 (119–257) | 222 (165–365) | 236 (211–450) | 225 ± 82 |
| WB effective half-life (h) | 51 (47–60) | 58 (53–65) | 59 (57–67) | 57 ± 5 |
| Serum A1 (%/L) | 8 (5–14) | 12 (6–23) | 13 (9–16) | 12 ± 5 |
| Serum α effective half-life (h) | 3.1 (1.2–5.7) | 5.0 (1.9–8.0) | 6.3 (2.2–8.9) | 5 ± 3 |
| Serum A2 (%/L) | 18 (15–27) | 18 (14–29) | 18 (13–27) | 19 ± 5 |
| Serum β effective half-life (h) | 19 (17–27) | 22 (19–27) | 28 (25–32) | 24 ± 5 |
Data are median, with range in parentheses.