TABLE 3

Longitudinal 18F-FDG PET and MRI Parameters (n = 17)

FMI parameterBaselineΔ post-IC1Δ post-IC2P*
MTV40% (cm3)
 Combined21.6 ± 16.4−70.9% ± 41.5%−76.4% ± 47.1%0.102
MTV3.5 (cm3)
 Combined33.3 ± 24.8−66.2% ± 40.8%−71.6% ± 45.0%0.362
TLG40% (g)
 Combined198.7 ± 171.4−71.3% ± 43.2%−75.1% ± 53.2%0.195
TLG3.5 (g)
 Combined261.3 ± 230.7−69.6% ± 42.4%73.0% ± 50.5%0.363
SUVmax (g/mL)
 Combined15.0 ± 6.3−37.1% ± 30.5%−46.9% ± 31.0%0.065
SUVmean (g/mL)
 Combined8.5 ± 3.8−23.8% ± 23.1%−30.8% ± 25.8%0.071
MR volume (cm3)
 Combined24.7 ± 18.7−50.7% ± 31.2%−60.6% ± 38.1%0.006
 Primary13.6 ± 16.5−68.0% ± 29.6%−77.8% ± 28.2%0.019
 LNs14.4 ± 12.8−36.8% ± 35.1%−48.4% ± 43.4%0.020
ADC (×10−3 mm2/s)
 Primary1.15 ± 0.1611.7% ± 20.2%18.5% ± 9.9%0.137
 LNs1.00 ± 0.1510.8% ± 16.9%12.4% ± 24.2%0.619
  • * Paired comparison between Δ post-IC1 and Δ post-IC2.

  • Significant.

  • Results reported as mean ± SD.

  • Δ post IC1 = (post-IC1 − baseline)/baseline × 100%; Δ post IC2 = (post-IC2 − baseline)/baseline × 100%.