TABLE 1

¹¹C-Metformin Kinetics

	K₁	k₂	k₃	k₄	V_d
Liver	0.32 (0.05)	0.24 (0.10)	0.07 (0.07)	0.07 (0.03)	2.45 (0.17)
Liver (dual input)	0.55 (0.15)	0.57 (0.39)	0.16 (0.14)	0.09 (0.03)	2.66 (0.23)
Intestines	0.22 (0.07)	1.22 (0.58)	0.07 (0.03)	0.02 (0.01)	0.90 (0.35)
Muscle	0.06 (0.02)	0.55 (0.36)	0.03 (0.02)	0.01 (0.00)	0.80 (0.42)
Kidney	ND	ND	ND	ND	6.83 (1.73)

ND = not determined.
Data are mean values, with SDs in parentheses.