Salivary Composition of Patients with DTC (n = 67) Treated with Ablation and Repeated Radioiodine Therapy
| Salivary parameter | Before radioiodine therapy | After radioiodine therapy | P |
| Ablation patients (n = 56) | |||
| Total protein (mg/min) | |||
| Unstimulated whole saliva (n = 44) | 0.18 (0.11–0.32) | 0.15 (0.09–0.21) | 0.031 |
| Chewing-stimulated whole saliva (n = 56) | 0.40 (0.27–0.61) | 0.32 (0.20–0.46) | 0.001 |
| Acid-stimulated parotid saliva (n = 41) | 0.05 (0.02–0.08) | 0.03 (0.02–0.06) | 0.101 |
| Acid-stimulated SM (n = 49) | 0.05 (0.02–0.08) | 0.04 (0.02–0.07) | 0.126 |
| Amylase (U/min) | |||
| Unstimulated whole saliva (n = 44) | 55.4 (27.9–111) | 37.7 (19.1–78.6) | 0.017 |
| Chewing-stimulated whole saliva (n = 56) | 161 (101–259) | 116 (48.4–192) | 0.006 |
| Acid-stimulated parotid saliva (n = 37) | 25.5 (11.0–46.7) | 16.2 (7.4–30.0) | 0.023 |
| Acid-stimulated SM (n = 48) | 11.7 (5.4–26.2) | 10.5 (4.3–20.2) | 0.028 |
| Repeated-treatment patients (n = 11) | |||
| Total protein (mg/min) | |||
| Unstimulated whole saliva (n = 9) | 0.13 (0.06–0.38) | 0.09 (0.06–0.27) | 0.859 |
| Chewing-stimulated saliva (n = 11) | 0.33 (0.19–0.49) | 0.26 (0.16–0.60) | 0.424 |
| Acid-stimulated parotid saliva (n = 7) | 0.05 (0.02–0.11) | 0.03 (0.01–0.09) | 0.600 |
| Acid-stimulated SM (n = 11) | 0.06 (0.04–0.13) | 0.03 (0.02–0.10) | 0.021 |
| Amylase (U/min) | |||
| Unstimulated whole saliva (n = 9) | 37.3 (16.0–136) | 20.8 (10.2–110) | 0.028 |
| Chewing-stimulated whole saliva (n = 11) | 131 (90.6–187) | 139 (6.4–266) | 0.328 |
| Acid-stimulated parotid saliva (n = 7) | 28.9 (9.3–57.9) | 20.7 (6.9–63.1) | 0.463 |
| Acid-stimulated SM (n = 11) | 11.6 (7.0 –48.2) | 5.3 (3.6–51.6) | 0.248 |
SM = submandibular gland saliva.
Numbers (n) of patients with valid paired measurements are indicated, dependent on saliva quantity. Data in parentheses are IQRs.