TABLE 1

Characteristics of Selected Studies

Reference	Country	n	Age (SD)	% male	Type of AC	Tracer	Test interval	CAD definition	AC sensitivity	AC specificity	NAC sensitivity	NAC specificity
Yamauchi (7)	Japan	150	70 (7)	68	SSPAC	^99mTc	3 mo	>50%	0.91	0.90	0.77	0.76
Patil (8)	United States	54	66 (11)	74	¹⁵³Gd	^99mTc	30 d	>70%	0.89	0.75
								LM > 50%
Sharma (18)	India	171	55 (10)	82	CT AC	^99mTc	3 mo	>50%	0.57	0.89	0.65	0.83
Genovesi (29)	Italy	104	64 (10)	79	CT AC	^99mTc	1 mo	>70%	0.75	0.81
								LM > 50%
Huang (30)	China	99	62 (12)	56	CT AC	^99mTc	60 d	>70%	0.92	0.79	0.95	0.63
Bateman (9)	United States	92	64 (12)	60	¹⁵³Gd	^99mTc	181 d	>70%	0.83	0.71	0.77	0.67
Wolak (10)	United States	114	65 (21)	0	¹⁵³Gd	^99mTc	60 d	>70%	0.81	0.73	0.80	0.73
Taneja (31)	United Kingdom	141	67 (-)^*	40	¹⁵³Gd	^99mTc	3 mo	>70%	0.71	0.91	0.61	0.83
Masood (19)	United States	118	61 (12)	67	CT AC	^99mTc	3 mo	>50%	0.94	0.59	0.93	0.56
Utsunomiya (32)	Japan	30	68 (-)^*	60	CT AC	²⁰¹Tl	30 d	>50%	0.76	0.93	0.67	0.86
Thompson (33)	United States	116	60 (11)	70	¹⁵³Gd	^99mTc	60 d	>70%	0.86	0.79	0.89	0.50
Banzo (34)	Spain	99	59 (-)^*	72	¹⁵³Gd	^99mTc	3 mo	>70%	0.76	0.71	0.92	0.46
Links (35)	United States	66	(-)^*	68	¹⁵³Gd	^99mTc	Trial period	>50%	0.96	0.85	0.78	0.62
					^99mTc	²⁰¹Tl	Trial period
Lee (20)	Korea	68	59 (12)	43	^99mTc	^99mTc	2 mo	>70%	0.74	0.75	0.67	0.59
Hendel (36)	United States	112	61 (12)	56	¹⁵³Gd	^99mTc	3 mo	>50%	0.78	0.44	0.76	0.50
Gallowitsch (37)	Austria	107	64 (10)	65	²⁴¹Am	²⁰¹Tl	1–14 d	>70%	0.94	0.91	0.79	0.80
Ficaro (17)	United States	60	63 (12)	63	²⁴¹Am	Dual tracer^†	90 d	>50%	0.88	0.82	0.84	0.46

↵* No available information in included study.
↵† ²⁰¹Tl for resting perfusion study and ^99mTc for stress perfusion study.
SSPAC = AC using segmentation with scatter and photopeak window data; LM = left main coronary artery.