18F-Florbetaben SUVRs by Cerebral Cortical Region, Type of Cerebellar Aβ Deposit, and Cerebellar Aβ score
| Score | ||||||||
| Scope | Region | Deposit | Absent | Sparse | Moderate | Frequent | Pdiffuse | Pvascular |
| Full sample | Frontal (n = 83) | Diffuse plaques | 1.36 ± 0.35 (1.29,1.43) | 1.70 ± 0.33 (1.62,1.77) | 1.82 ± 0.29 (1.76,1.89) | — | <10−4 | 0.003 |
| Vascular | 1.31 ± 0.35 (1.23,1.38) | 1.66 ± 0.34 (1.56,1.74) | 1.66 ± 0.33 (1.59,1.73) | 1.77 ± 0.24 (1.72,1.82) | ||||
| Occipital (n = 82) | Diffuse plaques | 1.44 ± 0.21 (1.40,1.49) | 1.66 ± 0.24 (1.61,1.71) | 1.69 ± 0.26 (1.64,1.75) | — | <10−4 | 0.001 | |
| Vascular | 1.41 ± 0.21 (1.36,1.46) | 1.63 ± 0.21 (1.59,1.68) | 1.65 ± 0.30 (1.58,1.71) | 1.66 ± 0.19 (1.62,1.70) | ||||
| AC (n = 82) | Diffuse plaques | 1.37 ± 0.40 (1.29,1.46) | 1.74 ± 0.38 (1.66,1.82) | 1.86 ± 0.31 (1.80,1.93) | — | <10−4 | 0.03 | |
| Vascular | 1.35 ± 0.37 (1.27,1.43) | 1.65 ± 0.45 (1.56,1.75) | 1.67 ± 0.43 (1.58,1.77) | 1.91 ± 0.18 (1.87,1.95) | ||||
| PC (n = 82) | Diffuse plaques | 1.59 ± 0.39 (1.51,1.67) | 1.87 ± 0.37 (1.79,1.95) | 1.86 ± 0.24 (1.81,1.92) | — | 0.004 | 0.13 | |
| Vascular | 1.56 ± 0.37 (1.48,1.64) | 1.80 ± 0.39 (1.72,1.89) | 1.81 ± 0.43 (1.72,1.90) | 1.96 ± 0.22 (1.91,2.01) | ||||
| Subsample | Frontal (n = 44) | Diffuse plaques | 1.64 ± 0.34 (1.54,1.74) | 1.77 ± 0.29 (1.69,1.85) | 1.73 ± 0.24 (1.66,1.80) | — | 0.47 | 0.83 |
| Vascular | 1.64 ± 0.33 (1.54,1.74) | 1.74 ± 0.32 (1.65,1.84) | 1.75 ± 0.26 (1.67,1.83) | 1.79 ± 0.28 (1.71,1.87) | ||||
| Occipital (n = 41) | Diffuse plaques | 1.67 ± 0.21 (1.60,1.73) | 1.68 ± 0.23 (1.61,1.75) | 1.60 ± 0.16 (1.55,1.65) | — | 0.77 | 0.08 | |
| Vascular | 1.50 ± 0.22 (1.43,1.56) | 1.68 ± 0.19 (1.62,1.74) | 1.74 ± 0.23 (1.67,1.81) | 1.74 ± 0.17 (1.68,1.79) | ||||
| AC (n = 26) | Diffuse plaques | 1.73 ± 0.39 (1.58,1.88) | 1.77 ± 0.36 (1.63,1.90) | 1.74 ± 0.18 (1.67,1.81) | — | 0.97 | 0.57 | |
| Vascular | 1.77 ± 0.16 (1.70,1.83) | 1.72 ± 0.48 (1.54,1.91) | 1.63 ± 0.18 (1.56,1.70) | 1.92 ± 0.21 (1.84,2.00) | ||||
| PC (n = 32) | Diffuse plaques | 1.91 ± 0.44 (1.77,2.06) | 1.94 ± 0.34 (1.82,2.06) | 1.79 ± 0.20 (1.72,1.86) | — | 2 | 0.96 | |
| Vascular | 1.90 ± 0.42 (1.76,2.05) | 1.90 ± 0.43 (1.75,2.05) | 1.89 ± 0.29 (1.79,1.99) | 1.98 ± 0.26 (1.89,2.07) | ||||
AC = anterior cingulate; PC = posterior cingulate.
Data are mean ± SD followed by 95% confidence interval in parentheses, with cerebellar cortex as reference region.