Factors Affecting Survival
| OS* | Disease-free survival* | |||||
| Variable | Events | HR (95% CI) | P | Events | HR (95% CI) | P |
| Menopausal status | ||||||
| No | 1/28 | 1 | 2/28 | 1 | ||
| Yes | 6/18 | 9.7 (1.1–84) | 0.035 | 6/18 | 5.4 (1.0–28) | 0.040 |
| Glucose metabolic response (ΔSUVmax cutoff = −50%) | ||||||
| Good metabolic response | 2/20 | 1 | 2/20 | 1 | ||
| Poor metabolic response | 5/20 | 3.1 (0.6–16) | NS | 5/20 | 3.0 (0.6–16) | NS |
| Unknown | 0/6 | 1/6 | ||||
| BF response (ΔBF cutoff = −30%) | ||||||
| Good BF response | 1/20 | 1 | 1/20 | 1 | ||
| Poor BF response | 6/20 | 9.6 (1.1–84) | 0.037 | 6/20 | 9.2 (1.1–80) | 0.040 |
| Unknown | 0/6 | 1/6 | ||||
| Type of surgery | ||||||
| Breast-conserving | 3/30 | 1 | 4/30 | 1 | ||
| Mastectomy | 4/16 | 4.7 (1.0–22) | 0.046 | 4/16 | 3.3 (0.8–14) | NS |
| Histologic response | ||||||
| pCR | 0/20 | NC | — | 1/20 | 1 | |
| Non-pCR | 7/26 | 7/26 | 6.7 (0.8–57) | NS | ||
| Histologic response + BF response (cutoff = −30%) | ||||||
| pCR | 0/20 | NC | — | 1/20 | 1 | |
| Non-pCR and good BF response | 1/10 | 1/10 | 1.4 (0.3–20) | NS | ||
| Non-pCR and poor BF response | 6/13 | 6/13 | 13 (1.5–116) | 0.017 | ||
| Unknown | 0/3 | 0/3 | ||||
↵* Univariate Cox proportional hazards model (patients with unknown variables were not included in the model).
Tumor size (>5 cm), American Joint Committee on Cancer staging, lymph node involvement, history of pregnancy, Scarf–Bloom–Richardson grading, tumor architectural differentiation, nuclear pleomorphism, number of mitosis, SUVmax1, BF1, and the SUVmax1/BF1 ratio were not associated with OS. Data in parentheses are 95% CIs.
HR = hazard ratio; NS = nonsignificant (P > 0.05); NC = not calculable.