TABLE 3

Effect of Treatment and Time on Apoptosis

Time after radiation
Parameter2 mo3 mo4 mo
Apoptosis
 % of lesion
  Section A
   No radiotracer0.021 ± 0.0670.506 ± 0.4561.881 ± 0.463†,‡
   18F-FDG0.003 ± 0.0040.484 ± 0.4641.971 ± 0.658†,‡
   99mTc-rhAnnexin V-1280.011 ± 0.0230.896 ± 0.515*2.197 ± 0.542†,‡
  Section B
   No radiotracer0.003 ± 0.0070.451 ± 0.5061.377 ± 0.516†,‡
   18F-FDG0.004 ± 0.0090.306 ± 0.4801.395 ± 0.609†,‡
   99mTc-rhAnnexin V-1280.016 ± 0.0230.590 ± 0.3751.594 ± 0.526†,‡
  Section C
   No radiotracer0.007 ± 0.0220.222 ± 0.2801.302 ± 0.550†,‡
   18F-FDG0.001 ± 0.0040.044 ± 0.0661.407 ± 0.422†,‡
   99mTc-rhAnnexin V-1280.018 ± 0.0180.389 ± 0.2851.416 ± 0.312†,‡
 Area (mm2)
  Section A
   No radiotracer0.000 ± 0.0000.001 ± 0.0010.009 ± 0.003†,‡
   18F-FDG0.000 ± 0.0000.001 ± 0.0010.010 ± 0.005†,‡
   99mTc-rhAnnexin V-1280.000 ± 0.0000.002 ± 0.0020.010 ± 0.002†,‡
  Section B
   No radiotracer0.000 ± 0.0000.001 ± 0.0010.004 ± 0.002†,‡
   18F-FDG0.000 ± 0.0000.001 ± 0.0010.005 ± 0.002†,‡
   99mTc-rhAnnexin V-1280.000 ± 0.0000.001 ± 0.0010.006 ± 0.002†,‡
  Section C
   No radiotracer0.00 ± 0.000.001 ± 0.0010.003 ± 0.002†,‡
   18F-FDG0.00 ± 0.000.000 ± 0.0000.004 ± 0.003†,‡
   99mTc-rhAnnexin V-1280.00 ± 0.000.001 ± 0.0000.004 ± 0.001†,‡

  • ↵* P < 0.01 (2 vs. 3 mo).

  • ↵† P < 0.001 (3 vs. 4 mo).

  • ↵‡ P < 0.001 (2 vs. 4 mo).

  • Data are mean ± SD.