TABLE 6

Multivariate Cox Regression Models for OS

	NG_35%		ORG_35%		NG_100%
Fixed input	Hazard ratio	P	Hazard ratio	P	Hazard ratio	P
Disease stage		0.1		0.1		0.1
I	1		1		1
II	0.2 (0.03–1.1)		0.2 (0.03–1.1)		0.2 (0.04–1.2)
III	1.7 (0.4–8.6)		1.4 (0.3–7.2)		1.8 (0.4–8.9)
IV	1.8 (0.3–12)		1.7 (0.2–12)		1.9 (0.3–13)
Treatment		<0.0001^*		<0.0001^*		<0.0001^*
Surgery	1		1		1
Chemoradiotherapy	0.3 (0.1–0.6)		0.3 (0.2–0.7)		0.4 (0.1–1.8)
Chemotherapy	1.1 (0.5–2.4)		1.1 (0.5–2.5)		1.6 (0.3–8.3)
Expectative (none)	5.2 (2.2–12)		4.5 (2.0–10)		7.7 (1.5–40)
Iterative backward selection
Summed TLG	1.07 (1.01–1.13)	0.02^*	1.08 (1.02–1.14)	0.009^*	1.07 (1.01–1.13)	0.04^*
High-intensity emphasis	0.997 (0.995–0.999)	0.02^*	0.997 (0.995–0.999)	0.02^*	0.997 (0.995–0.999)	0.02^*

↵* Statistically significant.
Data in parentheses are 95% confidence intervals. Hazard ratios are per 100-unit change for TLG and per 1-unit change for other parameters.