TABLE 2

Possible Risk Factors to Consider Before PRLT

Risk factor	Precaution
Severe bone marrow depression due to…
Disseminated metastases
Previous irradiation of spine or pelvis
Concurrent chemotherapy	Allow at least 6 wk before PRLT
²²³Ra therapy	Allow at least 2–3 mo before PRLT
Severe anemia^*	Correct by transfusion of packed red blood cells before PRLT
Severe renal insufficiency^†
Fixed postrenal obstruction	Correct by ureteral stenting or percutaneous nephrostomy before PRLT

↵* Hemoglobin level < 5.5 mmol/L.
↵† For example, after chemotherapy or in cases of obstructive or diabetic nephropathy.