Optimal PET-Based VOI Method for Each PVC Method, in Lung and Mediastinum
Location | Uncorrected | IDC-LR | HH-GLBL | HH-LCL | Spillover | PSF |
Mediastinum | A70PEAK (97 ± 4.1) | A50MAX (102 ± 2.7) | 50MAX (96 ± 2.4) | RTL (109 ± 2.6) | RTL (104 ± 2.0) | A70PEAK (99 ± 1.5) |
Lung | A70PEAK (90 ± 9.8) | A42MAX (99 ± 0.9) | 42MAX (109 ± 15.8) | 50MAX (103 ± 4.7) | A42MAX (105 ± 3.3) | A70PEAK (94 ± 6.0) |
IDC-LR = iterative deconvolution Lucy–Richardson PVC; HH-GLBL = global-background–adapted PVC; HH-LCL = local-background–adapted PVC; A70PEAK = 70% of peak voxel value adapted for local background uptake; A50MAX = 50% of maximal voxel value adapted for local background uptake; 50MAX = 50% of maximal voxel value; RTL = relative threshold level; A42MAX = 42% of maximal voxel value adapted for local background uptake; 42MAX = 42% of maximal voxel value.
Data are for noise-free simulated images. Mean accuracy (percentage ± SD) of spheres ≥ 15 mm is shown in parentheses.