Bmax and Kd Values for 3H-AV-1451 and 3H-MK-6240 Binding in Non-AD Brain Tissues
| 3H-AV-1451 | 3H-MK-6240 | |||||
| Donor tissue | Bmax (nM) | Kd (nM) | Bmax/Kd | Bmax (nM) | Kd (nM) | Bmax/Kd |
| Non-AD037 frontal cortex | 61 | 10.3 | 5.9 | Nonsaturable | Nonsaturable | Nonsaturable |
| Non-AD294 frontal cortex | 152 | 4.94 | 31 | Nonsaturable | Nonsaturable | Nonsaturable |
| Non-AD449 frontal cortex | 190 | 4.79 | 40 | Nonsaturable | Nonsaturable | Nonsaturable |
NDB was defined by self-block.