TABLE 1

Postmortem Tissue Counting in Rats at 10 Minutes, 30 Minutes, and 1 Hour After Injection of ¹⁸F-FDS and ^99mTc-DTPA

	¹⁸F-FDS			^99mTc-DTPA
Organ	10 min	30 min	1 h	10 min	30 min	1 h
Blood	0.61 ± 0.16	0.38 ± 0.03^*	0.15 ± 0.01^*	0.84 ± 0.18	0.34 ± 0.03	0.09 ± 0.02
Liver	0.54 ± 0.10^*	0.31 ± 0.03^*	0.11 ± 0.01^†	0.34 ± 0.09	0.15 ± 0.01	0.05 ± 0.01
Kidneys	1.77 ± 0.74	1.21 ± 0.09^*	0.53 ± 0.21	2.51 ± 0.97	1.50 ± 0.18	0.77 ± 0.27
Intestine	0.17 ± 0.05	0.15 ± 0.02^*	0.10 ± 0.01^†	0.14 ± 0.03	0.08 ± 0.03	0.04 ± 0.01
Muscle	0.14 ± 0.04^*	0.13 ± 0.03	0.05 ± 0.01^*	0.20 ± 0.04	0.16 ± 0.04	0.02 ± 0.01
Spleen	0.18 ± 0.05	0.22 ± 0.01^†	0.12 ± 0.01	0.16 ± 0.03	0.11 ± 0.01	0.10 ± 0.17
Stomach	0.08 ± 0.02	0.12 ± 0.06	0.03 ± 0.01	0.11 ± 0.03	0.12 ± 0.06	0.02 ± 0.01
Bone	0.14 ± 0.04	0.08 ± 0.01	0.05 ± 0.01^†	0.15 ± 0.04	0.07 ± 0.02	0.02 ± 0.01
Heart	0.26 ± 0.07	0.21 ± 0.01^*	0.13 ± 0.01^*	0.30 ± 0.07	0.14 ± 0.01	0.05 ± 0.03
Lung	0.47 ± 0.16	0.34 ± 0.06	0.17 ± 0.02^*	0.63 ± 0.24	0.31 ± 0.07	0.09 ± 0.06

↵* P < 0.05 vs. ^99mTc-DTPA.
↵† P < 0.0001 vs. ^99mTc-DTPA.
Data are %ID/g (mean value ± SD). Number of rats was 5 at 10 min, 4 at 30 min, and 5 at 1 h after tracer injection.