Test–Retest Reproducibility of Volume of Distribution and Binding Potential
| MA1 (t* = 40 min) | SRTM | |||||||||||
| VT (n = 5) | BPND (n = 5) | BPP (n = 5) | BPND (n = 5) | |||||||||
| Region | *aTRV | *TRV | †ICC | *aTRV | *TRV | †ICC | *aTRV | *TRV | †ICC | *aTRV | *TRV | †ICC |
| Putamen | 9% | −4% ± 11% | 0.23 [–0.64, 0.87] | 16% | 0% ± 23% | 0.58 [–0.33, 0.94] | 15% | −4% ± 24% | −0.01 [–0.76, 0.80] | 14% | −1% ± 22% | 0.64 [–0.24, 0.95] |
| Nucleus accumbens | 7% | −2% ± 10% | 0.66 [–0.20, 0.96] | 17% | 4% ± 22% | 0.15 [–0.69, 0.85] | 14% | 0% ± 23% | −0.17 [–0.83, 0.74] | 14% | 2% ± 18% | 0.17 [–0.68, 0.86] |
| Caudate | 7% | −3% ± 8% | 0.68 [–0.17, 0.96] | 18% | 2% ± 21% | 0.73 [–0.08, 0.97] | 14% | −3% ± 19% | 0.55 [–0.36, 0.94] | 15% | 2% ± 20% | 0.83 [0.19, 0.98] |
| Occipital cortex | 8% | −4% ± 8% | 0.77 [0.03, 0.97] | 12% | 0% ± 16% | 0.27 [–0.62, 0.88] | 13% | −5% ± 18% | 0.15 [–0.69, 0.85] | 15% | 3% ± 17% | 0.36 [–0.55, 0.91] |
| Centrum semiovale | 10% | −6% ± 11% | 0.71 [–0.12, 0.96] | 18% | −9% ± 19% | 0.63 [–0.26, 0.95] | 24% | −15% ± 22% | 0.53 [–0.38, 0.94] | 11% | −4% ± 14% | 0.71 [–0.11, 0.96] |
| Temporal cortex | 8% | −4% ± 9% | 0.71 [–0.12, 0.96] | 14% | −4% ± 24% | 0.57 [–0.34, 0.94] | 22% | −10% ± 28% | 0.15 [–0.69, 0.85] | 18% | −3% ± 26% | 0.51 [–0.41, 0.93] |
| Frontal cortex | 7% | −4% ± 7% | 0.75 [–0.03, 0.97] | 12% | −2% ± 16% | 0.85 [0.26, 0.98] | 13% | −7% ± 17% | 0.69 [–0.14, 0.96] | 15% | 5% ± 17% | 0.85 [0.26, 0.98] |
| Parietal cortex | 5% | −2% ± 7% | 0.84 [0.20, 0.98] | 21% | 6% ± 25% | 0.65 [–0.23, 0.96] | 22% | 2% ± 30% | 0.51 [–0.41, 0.93] | 21% | 9% ± 24% | 0.69 [–0.16, 0.96] |
| Cerebellum | 5% | −3% ± 6% | 0.90 [0.45, 0.99] | |||||||||
↵* TRV = (test value – retest value)/(test value + retest value) × 2, and aTRV is absolute value of TRV.
↵† ICC = (BSMSS – WSMSS)/(BSMSS + WSMSS) where BSMSS is mean sum of squares between subjects and WSMSS is mean sum of squares within subjects. ICC is presented with lower and upper bounds of 95% confidence interval in brackets.