Absolute Detection Efficiency and Detection Limit for Microfluidic and Catheter-Based Detectors
Chip 1 (0.66 μL) | Chip 2* (1.46 μL) | PE10 (1.85 μL) | PE50 (7.93 μL) | |||||||
Isotope | Eβmean (keV) | β/CE emission probability (%) | η (cps/Bq) | Amin – Amax (Bq/μL) | η (cps/Bq) | Amin – Amax (Bq/μL) | η (cps/Bq) | Amin – Amax (Bq/μL) | η (cps/Bq) | Amin – Amax (Bq/μL) |
64Cu | 190, 278 | 37.2, 17.8 | 20% | 100–5.0⋅105 | 20% | 45–2.3⋅105 | 3% | 254–1.3⋅106 | 2% | 93–4.6⋅105 |
18F | 250 | 96.7 | 39% | 51–2.5⋅105 | 39% | 23–1.2⋅105 | 7% | 103–5.1⋅105 | 4% | 38–1.9⋅105 |
11C | 386 | 99.8 | 47% | 42–2.1⋅105 | 47% | 19–9.6⋅104 | 15% | 46–2.3⋅105 | 12% | 14–6.9⋅104 |
68Ga | 353, 836 | 1.2, 87.7 | 43% | 47–2.3⋅105 | 43% | 21–1.1⋅105 | 22% | 33–1.6⋅105 | 17% | 10–4.9⋅104 |
99mTc | 120, 138 | 8.8, 1 | 4% | 527–2.6⋅106 | 4% | 238–1.2⋅106 | 0.2% | 4,447–2.2⋅107 | 0.2% | 1,034–5.2⋅106 |
↵* Estimated.
Eβmean = mean energy of β-particles.
Detection volume is indicated in brackets for each device. Data for microfluidic Chip 2 were computed.