Minimum and Maximum Radiopharmaceutical Dosages in Smaller and Larger Patients, Respectively, According to Familiarity of Site with 2010 Guidelines
| Dosage* | |||||||||
| Familiar with guidelines? | n | Minimum | Mean | SD | Median | Maximum | Factor of variation (max/min) | Guideline-recommended dosage* | Respondents following guideline ± 20% |
| Minimum dose in smaller patients | |||||||||
| 99mTc-MDP | |||||||||
| Total | 35 | 18.50 (0.50) | 51.27 (1.39) | 35.07 (0.95) | 37.00 (1.00) | 185.00 (5.00) | 10.00 | 37.00 (1.00) | 71.4% |
| No | 9 | 37.00 (1.00) | 71.94 (1.94) | 39.73 (1.07) | 74.00 (2.00) | 148.00 (4.00) | 4.00 | 44.4% | |
| Yes | 21 | 18.50 (0.50) | 39.64 (1.07) | 12.11 (0.33) | 37.00 (1.00) | 74.00 (2.00) | 4.00 | 85.7% | |
| 99mTc-MAG3 | |||||||||
| Total | 39 | 18.50 (0.50) | 37.47 (1.01) | 15.00 (0.41) | 37.00 (1.00) | 111.00 (3.00) | 6.00 | — | — |
| No | 9 | 18.50 (0.50) | 32.89 (0.89) | 8.16 (0.22) | 37.00 (1.00) | 37.00 (1.00) | 2.00 | ||
| Yes | 26 | 18.50 (0.50) | 37.71 (1.02) | 16.11 (0.44) | 37.00 (1.00) | 111.00 (3.00) | 6.00 | ||
| 99mTc-DMSA | |||||||||
| Total | 33 | 18.50 (0.50) | 32.07 (0.87) | 26.63 (0.72) | 18.50 (0.50) | 111.00 (3.00) | 6.00 | 18.5 (0.50) | 63.6% |
| No | 10 | 18.50 (0.50) | 35.15 (0.95) | 28.19 (0.76) | 27.75 (0.75) | 111.00 (3.00) | 6.00 | 50.0% | |
| Yes | 22 | 18.50 (0.50) | 30.44 (0.82) | 27.04 (0.73) | 18.50 (0.50) | 111.00 (3.00) | 6.00 | 72.7% | |
| 99mTc-HIDAs | |||||||||
| Total | 22 | 18.50 (0.50) | 28.59 (0.77) | 13.66 (0.37) | 18.50 (0.50) | 74.00 (2.00) | 4.00 | 18.5 (0.50) | 54.6% |
| No | 7 | 18.50 (0.50) | 29.07 (0.79) | 9.89 (0.27) | 37.00 (1.00) | 37.00 (1.00) | 2.00 | 42.9% | |
| Yes | 14 | 18.50 (0.50) | 27.75 (0.75) | 15.81 (0.43) | 18.50 (0.50) | 74.00 (2.00) | 4.00 | 64.3% | |
| 18F-FDG | |||||||||
| Total | 16 | 18.50 (0.50) | 63.59 (1.72) | 72.75 (1.97) | 37.00 (1.00) | 296.00 (8.00) | 16.00 | 37.00 (1.00) | 75.0% |
| No | 2 | 37.00 (1.00) | 166.5 (4.50) | 183.14 (4.95) | 166.50 (4.50) | 296.00 (8.00) | 8.00 | 50.0% | |
| Yes | 13 | 18.50 (0.50) | 49.81 (1.35) | 42.31 (1.14) | 37.00 (1.00) | 185.00 (5.00) | 10.00 | 76.9% | |
| Maximum dose in larger patients | |||||||||
| 99mTc-MDP | |||||||||
| Total | 50 | 444.00 (12.00) | 788.92 (21.32) | 152.01 (4.11) | 740.00 (20.00) | 1110.00 (30.00) | 2.50 | — | — |
| No | 16 | 444.00 (12.00) | 797.81 (21.56) | 136.43 (3.69) | 740.00 (20.00) | 925.00 (25.00) | 2.08 | ||
| Yes | 26 | 444.00 (12.00) | 770.04 (20.81) | 172.96 (4.67) | 740.00 (20.00) | 1,110.00 (30.00) | 2.50 | ||
| 99mTc-MAG3 | |||||||||
| Total | 42 | 111.00 (3.00) | 266.05 (7.19) | 115.64 (3.13) | 240.50 (6.50) | 555.00 (15.00) | 5.00 | — | — |
| No | 11 | 148.00 (4.00) | 299.36 (8.09) | 99.91 (2.70) | 370.00 (10.00) | 370.00 (10.00) | 2.50 | ||
| Yes | 27 | 111.00 (3.00) | 246.67 (6.67) | 119.23 (3.22) | 185.00 (5.00) | 555.00 (15.00) | 5.00 | ||
| 99mTc-DMSA | |||||||||
| Total | 35 | 74.00 (2.00) | 178.68 (4.83) | 54.74 (1.48) | 185.00 (5.00) | 370.00 (10.00) | 5.00 | — | — |
| No | 11 | 74.00 (2.00) | 164.82 (4.45) | 44.90 (1.21) | 185.00 (5.00) | 222.00 (6.00) | 3.00 | ||
| Yes | 22 | 74.00 (2.00) | 183.35 (4.96) | 60.63 (1.64) | 185.00 (5.00) | 370.00 (10.00) | 5.00 | ||
| 99mTc-HIDAs | |||||||||
| Total | 26 | 111.00 (3.00) | 186.45 (5.04) | 43.40 (1.17) | 185.00 (5.00) | 296.00 (8.00) | 2.67 | — | — |
| No | 8 | 148.00 (4.00) | 194.25 (5.25) | 43.10 (1.16) | 185.00 (5.00) | 296.00 (8.00) | 2.00 | ||
| Yes | 15 | 129.50 (3.50) | 180.12 (4.87) | 33.06 (0.89) | 185.00 (5.00) | 259.00 (7.00) | 2.00 | ||
| 18F-FDG | |||||||||
| Total | 20 | 185.00 (5.00) | 407.74 (11.02) | 137.33 (3.71) | 370.00 (10.00) | 666.00 (18.00) | 3.60 | — | — |
| No | 5 | 370.00 (10.00) | 458.80 (12.40) | 92.87 (2.51) | 444.00 (12.00) | 555.00 (15.00) | 1.50 | ||
| Yes | 14 | 185.00 (5.00) | 378.99 (10.24) | 146.11 (3.95) | 370.00 (10.00) | 666.00 (18.00) | 3.60 | ||
↵* Units of measurement are megabecquerels (MBq) followed by millicuries (mCi) in parentheses.
n indicates number of respondents. In some cases, numbers answering “no” and “yes” do not equal total number because not all sites indicated whether they are familiar with 2010 guidelines.