GLP-1 Receptor IC50 Values for Different GLP-1 Receptor Agonists and Antagonists
| Compound | Ligand/metal complex | Human insulinoma (nM) | Rat insulinoma (nM) |
| GLP-1(7-36) control | Ligand | 1.1 ± 0.3 | 0.8 ± 0.1 |
| Ex(9-39)NH2 | Ligand | 10.9 ± 1.1 | 3.9 ± 1.7 |
| [Nle14,Lys40(Ahx-DOTA)NH2]Ex-4 | Ligand | 0.9 ± 0.3 | 0.5 ± 0.2 |
| [Lys40(Ahx-DOTA)NH2]-Ex(9-39) | Ligand | 44.1 ± 7.0 | 8.5 ± 3.0 |
| [Lys27(Ahx-DOTA)]-Ex(9-39)NH2 | Ligand | 48.1 ± 5.1 | 122.3 ± 12.1 |
| natGa | 137.2 ± 10.3 | 213.2 ± 21.3 | |
| [Lys40(NODAGA)NH2]Ex(9-39) | Ligand | 29.7 ± 10.7 | 16.3 ± 3.6 |
| natGa | 46.7 ± 16.3 | 22.0 ± 5.3 | |
| [Lys27(NODAGA)]-Ex(9-39)NH2 | Ligand | 143.3 ± 56.6 | 81.0 ± 8.9 |
| natGa | 71.3 ± 26.5 | 46.7 ± 9.3 |