Overview of Patients Presenting with New 18F-FET Uptake in Follow-up
| Patient no. | Initial WHO grade | Initial treatment | Mo until 18F-FET positivity | TBRmax | TTPmin | Concurrent signs of progression | Concurrent malignant transformation | New WHO grade | Evaluation by | Subsequent malignant transformation |
| 1 | II | Surgical resection | 56.7 | 1.46 | 35.0 | Yes | No | II | Histology (biopsy) | None |
| 2 | II | Brachytherapy | 40.4 | 1.68 | 35.0 | No | No | II | Histology (biopsy) | None |
| 3 | II | Temozolomide | 53.1 | 1.62 | 35.0 | Yes | No | Not available | MRI/clinical course | None |
| 4 | II | Watch-and-wait | 49.1 | 1.74 | 35.0 | Yes | No | II | Histology (surgery) | None |
| 5 | II | Watch-and-wait | 21.6 | 2.33 | 35.0 | Yes | No | II | Histology (surgery) | After 7.1 mo |
| 6 | II | Surgical resection | 27.1 | 1.63 | 22.5 | Yes | No | III | Histology (surgery) | After 14.0 mo |
| 7 | II | Watch-and-wait | 29.7 | 3.73 | 12.5 | Yes | Yes | Not available | MRI | — |
| 8 | II | Watch-and-wait | 19.6 | 1.56 | 12.5 | No | No | II | Histology (surgery) | After 5.1 mo |
| 9 | II | Radiochemotherapy | 32.5 | 2.55 | 17.5 | Yes | Yes | III | Histology (biopsy) | — |
| 10 | II | Brachytherapy | 11.0 | 3.64 | 35.0 | Yes | Yes | IV | Histology (biopsy) | — |
| 11 | II | Watch-and-wait | 50.6 | 4.14 | 35.0 | Yes | Yes | IV | Histology (surgery) | — |
| 12 | II | Brachytherapy | 10.7 | 3.12 | 12.5 | Yes | Yes | IV | Histology (biopsy) | — |
| 13 | II | Surgical resection | 70.4 | 1.70 | 35.0 | Yes | Yes | III | Histology (surgery) | — |
| 14 | II | Watch-and-wait | 8.0 | 3.92 | 17.5 | Yes | Yes | IV | Histology (biopsy) | — |
| 15 | II | Brachytherapy | 62.7 | 3.20 | 17.5 | Yes | Yes | IV | Histology (biopsy) | — |
| 16 | II | Radiochemotherapy | 35.0 | 3.10 | 17.5 | Yes | Yes | IV | Histology (surgery) | — |
| 17 | II | Watch-and-wait | 12.3 | 1.82 | 12.5 | Yes | Yes | IV | Histology (biopsy) | — |
| 18 | II | Surgical resection | 6.9 | 2.74 | 17.5 | No | No | II | Histology (biopsy) | After 8.4 mo |
| 19 | II | Radiochemotherapy | 41.8 | 4.16 | 17.5 | No | Yes | III | Histology (biopsy) | — |
| 20 | II | Surgical resection | 41.7 | 2.37 | 17.5 | Yes | No | II | Histology (surgery) | After 9.0 mo |