TABLE 2

Hepatobiliary Secretion Kinetics Calculated for 11C-CSar from Blood Measurements

Q (mL blood/min/mL liver tissue)E0PSmem (mL blood/min/mL liver tissue)EssClint (mL blood/min/mL liver tissue)Clsys (mL blood/min/mL liver tissue)
PigsWeighted mean95% CIWeighted mean95% CIWeighted mean95% CIWeighted mean95% CIWeighted mean95% CIWeighted mean95% CI
Without CHD catheter0.820.76 to 0.880.990.988 to 0.9923.633.15 to 4.120.970.94 to 0.992.791.95 to 3.630.790.71 to 0.86
With CHD catheter1.01*0.90 to 1.110.96†0.958 to 0.9633.532.98 to 4.090.79†0.59 to 0.991.70‡0.73 to 2.660.810.60 to 1.02

  • ↵* P < 0.05 in comparison with data from pigs without CHD catheter.

  • ↵† P < 0.01 in comparison with data from pigs without CHD catheter.

  • ↵‡ P < 0.001 in comparison with data from pigs without CHD catheter.