TABLE 1

Paired-Label Biodistribution of ¹⁸F-RL-I-5F7 and ¹²⁵I-SGMIB-5F7 in Severe Combined Immunodeficiency Mice Bearing BT474M1 Xenografts

	%ID/g^*
	1 h		2 h
Tissue	¹²⁵I-SGMIB	¹⁸F-RL-I-5F7	¹²⁵I-SGMIB	¹⁸F-RL-I-5F7
Liver	3.27 ± 0.61	3.42 ± 0.57^†	3.12 ± 0.94	3.17 ± 1.13^†
Spleen	2.01 ± 0.62	1.63 ± 0.51	1.85 ± 0.49	1.31 ± 0.40
Lung	10.47 ± 2.27	9.07 ± 1.06^†	8.03 ± 0.83	6.63 ± 1.46^†
Heart	1.43 ± 0.47	1.30 ± 0.53^†	0.62 ± 0.15	0.54 ± 0.14^†
Kidney	122.68 ± 18.03	139.45 ± 20.54	96.92 ± 30.55	105.02 ± 39.52^†
Stomach	1.91 ± 0.77	1.97 ± 0.78^†	0.59 ± 0.28	0.54 ± 0.23^†
Small intestine	1.71 ± 0.52	2.10 ± 0.59	0.94 ± 0.30	1.28 ± 0.42
Large intestine	1.36 ± 0.31	1.68 ± 0.37	1.89 ± 1.30	2.47 ± 1.63
Muscle	1.16 ± 0.48	1.27 ± 0.50	0.91 ± 0.30	1.10 ± 0.38^†
Blood	1.75 ± 0.84	1.95 ± 0.87	0.65 ± 0.41	0.83 ± 0.43
Bone	0.76 ± 0.37	0.97 ± 0.31	0.78 ± 0.23	1.13 ± 0.28
Brain	0.10 ± 0.04	0.11 ± 0.04	0.07 ± 0.01	0.07 ± 0.02^†
Tumor	26.36 ± 3.12	28.97 ± 3.88	32.52 ± 12.11	36.28 ± 14.10

↵* Mean ± SD (n = 5).
↵† Difference in uptake not statistically significant.