Patient Characteristics and Overview of Scans Obtained
| Group | Patient no. | Age (y)/sex | Tumor EGFR mutational status | 11C-erlotinib scan 1/scan 2 | 15O-H2O scan 1/scan 2 |
| 1 | 1 | 61/male | Wild-type | Yes/yes | Yes/yes |
| 1 | 2 | 57/male | Wild-type | Yes/yes | Yes/failed |
| 1 | 3 | 59/female | Wild-type | Yes/yes | Yes/yes |
| 1 | 4 | 48/female | Wild-type | Yes/yes | Yes/yes |
| 1 | 5 | 65/male | Exon 20 ins (D770-N771(ins GG) + N771T) | Yes/yes | Yes/yes |
| 1 | 6 | 64/female | Exon 20 (G779S) + Kras exon1 (c.37 G > T, pG13C) | Yes/no | Yes/no |
| 1 | 7 | 69/female | Wild-type | Yes/no | Yes/no |
| 1 | 8 | 47/female | Wild-type | Yes/yes | Yes/yes |
| 1 | 9 | 79/female | Exon 20 ins (V769-D770 (ins ASV)) | Moved/no | Moved/no |
| 1 | 10 | 74/male | Wild-type | Yes/no | Yes/no |
| 2 | 11 | 48/female | Exon 21 point mutation (L858R) | Yes/no | Yes/no |
| 2 | 12 | 46/female | Exon 19 deletion (delE746-A750) | Yes/yes | Yes/yes |
| 2 | 13 | 47/male | Exon 19 deletion (delL747-T751) | Yes/yes | Yes/yes |
| 2 | 14 | 51/female | Exon 19 deletion (delE746-A750) + exon 20 (T790 M) | Yes/yes | Yes/yes |
| 2 | 15 | 37/female | Exon 19 deletion (delE746-A750) | No/yes | No/yes |
| 2 | 16 | 54/female | Exon 19 deletion (delE746-A750) | Yes/yes | Yes/yes |
| 2 | 17 | 68/female | Exon 19 deletion (delE746-S752) | Yes/no | Yes/no |
Patients were divided into different groups, according to presence of activating EGFR mutations.