Hematology and Serum Biochemistry in CD-1 Athymic Mice with Subcutaneous MDA-MB-468 Human BC Xenografts at 15 Days After Intratumoral Injection of 177Lu-T-AuNP, Unlabeled T-AuNP, or Normal Saline
| Parameter | Normal saline | Unlabeled T-AuNP | 177Lu-T-AuNP (0.3 MBq) | 177Lu-T-AuNP (1.5 MBq) | 177Lu-T-AuNP (4.5 MBq) |
| White blood cells (× 109/L) | 5.9 ± 2.9 | 7.0 ± 3.3 | 5.3 ± 2.7 | 5.4 ± 3.2 | 4.9 ± 1.6 |
| Red blood cells (× 1012/L) | 9.1 ± 0.8 | 9.3 ± 0.5 | 8.0 ± 1.0 | 10.0 ± 0.9 | 9.9 ± 0.7 |
| Hemoglobin (g/L) | 13.7 ± 1.1 | 13.8 ± 0.4 | 12.2 ± 0.6 | 14.5 ± 0.8 | 14.6 ± 1.0 |
| Hematocrit (%) | 43.0 ± 3.7 | 44.5 ± 2.1 | 39.1 ± 2.7 | 47.9 ± 3.9 | 47.7 ± 3.5 |
| ALT (U/L) | 33.5 ± 19.3 | 18.8 ± 3.9 | 21.4 ± 0.6 | 25.5 ± 17.3 | 17.8 ± 8.6 |
| Serum creatinine (μmol/L) | 15.4 ± 5.7 | 16.1 ± 8.0 | 27.4 ± 26.9 | 22.1 ± 10.6 | 18.2 ± 7.0 |
Values represent mean ± SD (n = 3–6).