TABLE 3

¹¹C-PBR28 and (R)-¹¹C-PK11195 Binding Potential (Mean ± SD) of Control and HSE Rats

	¹¹C-PBR28			(R)-¹¹C-PK11195
Brain region	Control	HSE	d	Control	HSE	d
Amygdala	1.24 ± 0.12	2.03 ± 0.48^*	2.3	1.67 ± 0.35	1.84 ± 0.54
Cerebellum	1.94 ± 0.34	3.00 ± 0.70^*	1.9	2.10 ± 0.53	2.09 ± 0.57
Cortex frontal	1.55 ± 0.45	2.61 ± 0.93		1.90 ± 0.61	2.01 ± 0.59
Hippocampus	1.08 ± 0.26	2.00 ± 0.63^†	1.9	1.42 ± 0.30	1.83 ± 0.63
Hypothalamus	1.12 ± 0.27	1.69 ± 0.34^*	1.9	1.63 ± 0.35	1.42 ± 0.50
Medulla	1.43 ± 0.26	3.95 ± 0.55^‡	5.9	1.74 ± 0.30	2.30 ± 0.25^†	2.0
Midbrain	1.12 ± 0.27	2.26 ± 0.52^‡	2.8	1.62 ± 0.60	2.20 ± 0.81
Pons	1.30 ± 0.42	3.19 ± 0.42^‡	5.0	1.88 ± 0.45	2.05 ± 0.66
Septum	1.19 ± 0.42	1.87 ± 0.55		1.67 ± 0.35	1.49 ± 0.57
Striatum	1.04 ± 0.24	1.87 ± 0.55		1.22 ± 0.29	1.30 ± 0.53
Thalamus	1.05 ± 0.24	1.81 ± 0.60^*	1.7	1.29 ± 0.30	1.68 ± 0.43
Whole brain	1.53 ± 0.36	2.63 ± 0.47^†	2.6	1.48 ± 0.33	1.73 ± 0.60

↵* P < 0.05.
↵† P < 0.01.
↵‡ P < 0.001.
d =Cohen’s effect size.