TABLE 9

Multivariate Analysis for Survival

CategoryHazard ratioP
Bilirubin < 1.3 mg/dL1.23 (0.80–1.87)0.349
Albumin > 3 g/dL0.47 (0.35–0.63)<0.001
ECOG 00.60 (0.46–0.79)<0.001
≤2 cytotoxic agents0.61 (0.46–0.79)<0.001
No biologics0.93 (0.68–1.28)0.663
Tumor burden ≤ 25%0.37 (0.28–0.49)<0.001
Extrahepatic disease absent0.50 (0.38–0.64)<0.001
Stage IV* at diagnosis0.88 (0.69–1.13)0.33
  • * American Joint Committee on Cancer criteria.

  • Ranges in parentheses are 95% CI.