TABLE 1

99mTc-Duramycin Tumor Uptake and Tumor-to-Background Ratios in Mice Bearing COLO205 Tumors After Chemotherapy

Treatment99mTc-Duramycin tumor uptake (%ID/mL)Tumor-to-muscle ratioTumor-to-blood ratio
Vehicle0.92 ± 0.061.6 ± 0.21.5 ± 0.2
Oxaliplatin, 5 mg/kg1.19 ± 0.123.6 ± 0.31.6 ± 0.2
Irinotecan, 100 mg/kg1.62 ± 0.074.6 ± 0.52.4 ± 0.4
Irinotecan, 80 mg/kg, plus oxaliplatin, 5 mg/kg2.61 ± 0.468.4 ± 0.93.4 ± 0.3
Blocking0.89 ± 0.092.0 ± 0.21.8 ± 0.2