99mTc-Duramycin Tumor Uptake and Tumor-to-Background Ratios in Mice Bearing COLO205 Tumors After Chemotherapy
Treatment | 99mTc-Duramycin tumor uptake (%ID/mL) | Tumor-to-muscle ratio | Tumor-to-blood ratio |
Vehicle | 0.92 ± 0.06 | 1.6 ± 0.2 | 1.5 ± 0.2 |
Oxaliplatin, 5 mg/kg | 1.19 ± 0.12 | 3.6 ± 0.3 | 1.6 ± 0.2 |
Irinotecan, 100 mg/kg | 1.62 ± 0.07 | 4.6 ± 0.5 | 2.4 ± 0.4 |
Irinotecan, 80 mg/kg, plus oxaliplatin, 5 mg/kg | 2.61 ± 0.46 | 8.4 ± 0.9 | 3.4 ± 0.3 |
Blocking | 0.89 ± 0.09 | 2.0 ± 0.2 | 1.8 ± 0.2 |