Pharmacokinetic Properties of 18F-THK-5351 and 18F-THK-5451 in Mice
| Time after injection (min) | Brain-to-blood ratio | Brain uptake ratio* |
| 18F-THK-5351 | ||
| 10 | 1.1 | 4.0 |
| 30 | 0.8 | 21 |
| 60 | 1.0 | 33 |
| 120 | 1.1 | 38 |
| 18F-THK-5451 | ||
| 10 | 1.1 | 2.4 |
| 30 | 0.8 | 4.9 |
| 60 | 0.8 | 6.1 |
| 120 | 0.9 | 6.6 |
↵* Calculated as ratio of values at 2 min to those at each specified time.