Median Survival Time and Significance of Prognostic Factors for OS
| Univariate | Multivariate with TLR | |||
| Variable | P | Median (mo) | P | Hazard ratio (95% confidence interval) |
| Age (y) | 0.779 | |||
| ≤60 | 13.3 | |||
| >60 | 11.4 | |||
| Sex | 0.583 | |||
| Men | 12.4 | |||
| Women | 11.4 | |||
| Etiology | 0.274 | |||
| HBV | 10.7 | |||
| HCV | 14.8 | |||
| Alcohol | 12.6 | |||
| Other | 23.8 | |||
| Child-Pugh classification | 0.026 | |||
| A | 13.3 | |||
| B | 7.7 | 0.018 | 1.60 (1.06–2.40) | |
| Treatment | 0.280 | |||
| TACE | 11.8 | |||
| CCRT | 13.7 | |||
| Tumor size (cm) | 0.006 | |||
| ≤6.0 | 22.9 | |||
| >6.0 | 10.0 | 0.257 | ||
| Tumor number | 0.890 | |||
| Single | 10.7 | |||
| Multiple | 13.3 | |||
| Portal vein thrombosis | 0.012 | |||
| Absence | 21.0 | |||
| Presence | 9.9 | 0.248 | ||
| Serum AFP (ng/dL) | 0.004 | |||
| ≤500.0 | 21.0 | |||
| >500.0 | 9.9 | 0.197 | ||
| TLR | <0.001 | |||
| ≤2.0 | 23.8 | |||
| >2.0 | 9.1 | <0.001 | 1.97 (1.43–2.72) | |
HBV = hepatitis B virus; HCV = hepatitis C virus.