TABLE 2

Model Results from Using 1.7 L of Intraperitoneally Infused Radiolabeled mAbs in Osmotic Agent

				Equivalent dose (Sv) (RBE, 5 for α-particles and 1 for electrons)
		Tumor (from cell-bound mAbs)			Tumor (total)
Nuclide	Fraction of mAbs radiolabeled	Administered activity (MBq)	Decays per cell (n)	Bone marrow	Peritoneal fluid	D, 18 μm	D, 60 μm	D, 100 μm	D, 18 μm	D, 60 μm	D, 100 μm
¹⁷⁷Lu	1/270	3,900	2,561	0.94	17	0.43	0.34	0.30	8.9	8.8	8.8
⁹⁰Y	1/270	1,100	2,580	0.61	26	0.13	0.12	0.12	13	13	13
¹⁸⁸Re	1/270	6,300	2,561	1.02	68	0.22	0.18	0.17	34	34	34
²¹¹At	1/200	300	2,602	0.14	24	231	278	264	244	292	275
²¹³Bi	1/200	3,000	953	0.02	43	71	80	93	94	104	114
²¹²Pb	1/200	300	2,995	0.36	37	244	283	288	264	305	305