Patient Demographics and Imaging Parameters
| Cohort group | |||
| Variable | Cases, first half* (n = 16) | Cases, second half* (n = 14) | Unmatched controls† (n = 8) |
| Age (y) | 58 (38–69) | 57 (40–72) | 56 (44–69) |
| Mass (kg) | 72 (50–116) | 70 (54–116) | 74 (59–92) |
| Tumor type | N/A | ||
| DCIS | 5 (31) | 5 (33) | |
| IDC‡ | 6 (38) | 5 (33) | |
| ILC‡ | 5 (31) | 5 (33) | |
| Longest dimension (mm) | |||
| DCIS | 25 (18–59) | 21 (4–61) | N/A |
| IDC‡ | 22 (3–24) | 12 (12–26) | |
| ILC‡ | 30 (12–75) | 18 (12–55) | |
| Acquisition time (min) | |||
| Ipsilateral | 13.9 (13.9–13.9) | 13.9 (13.9–13.9) | N/A |
| Contralateral/unmatched control | 7.0 (7.0–13.9) | 9.9 (7.0–13.9) | 7.0 (4.9–7.0) |
| Ainj (MBq) | 200 (189–218) | 96.2 (92.5–104) | 599 (566–611) |
| Aeff (MBq)§ | |||
| Ipsilateral | 399 (377–432) | 193 (181–205) | N/A |
| Contralateral and unmatched control | 197 (188–400) | 133 (96–196) | 571 (422–602) |
| Postinjection time (min) | |||
| 60-min image (ipsilateral) | 59 (51–71) | 60 (55–72) | N/A |
| 120-min image (ipsilateral) | 118 (90–131) | 119 (116–123) | N/A |
| Contralateral controls | 137 (131–180) | 153 (135–174) | N/A |
| Unmatched controls | N/A | N/A | 111 (79–153) |
| Counts (per 1,000) | |||
| 60-min image (ipsilateral) | 1,673 (1,083–5,605) | 955 (463–1,735) | N/A |
| 120-min image (ipsilateral) | 1,017 (710–3,980) | 609 (243–987) | N/A |
| Contralateral controls | 323 (247–680) | 274 (156–494) | N/A |
| Unmatched controls | N/A | N/A | 974 (674–2,390) |
↵* 12 of 30 (7 from 93-MBq group and 5 from 185-MBq group) had contralateral imaging.
↵† 9 control breasts from 8 patients were imaged using older protocol with injected activity of 592 MBq; craniocaudal and mediolateral oblique views were acquired for each breast except for 1 patient with only MLO view.
↵‡ One patient in 93-MBq group had both IDC and ILC in same breast.
↵§ Aeff, Equation 1.
N/A = not applicable.
Values are median, with range in parentheses.