Category | Potential uses | Examples in breast cancer |
Prognostic | Distinguish tumors with intrinsically good or poor prognosis | ER (4), HER2 (4), Oncotype DX 21-gene panel (23), circulating tumor cells (29) |
Predictive | Determine which therapies will be effective for individual patient | ER (13), HER2 (14) |
Pharmacodynamic | Determine dosing of novel systemic therapies for clinical trials | 18F-FES (84,85) |