Per-Lesion Analysis (Prostate Cancer)

Lesion typeExaminationSensitivitySpecificityPPVNPVAccuracy
Extraskeletal lesions18F/18F-FDG PET/CT100.0NA100.0NA100.0
Whole-body MRI100.0NA100.0NA100.0
18F/18F-FDG PET/CT + whole-body MRI100.0NA100.0NA100.0
Skeletal lesions (osteoblastic)18F/18F-FDG PET/CT100.0*60.094.1100.094.6
Whole-body MRI65.440.
Bone scintigraphy81.3100.0100.045.583.8
Bone scintigraphy + whole-body MRI100.040.088.5100.089.3
18F/18F-FDG PET/CT + whole-body MRI100.00.082.1NA82.1
Total lesions18F/18F-FDG PET/CT100.060.094.4100.094.9
Whole-body MRI76.040.086.425.070.0
Bone scintigraphy + whole-body MRI100.040.089.3100.090.0
18F/18F-FDG PET/CT + whole-body MRI100.00.083.3NA83.3
  • NA = not applicable. 18F/18F-FDG PET/CT showed significantly higher sensitivity than whole-body MRI (*P < 0.02) and bone scintigraphy (P < 0.03) in evaluation of skeletal lesions. 18F/18F-FDG PET/CT showed statistically significant higher sensitivity than whole-body MRI (P < 0.02)