Methods to Incorporate Molecular Images into Radiation Therapy Planning and Their Respective Degrees of Complexity
| Complexity | Registration | Segmentation | Target definition | Motion management |
| Basic | Manual alignment | Manual | Boundary definition | None (phase-averaged) |
| Rigid/affine | Threshold-based | Subvolume boost | Gated imaging and delivery | |
| Advanced | Deformable | Automatic algorithms | Voxelwise dose painting | 4D imaging and delivery |