Demographic and Smoking-Related Variables at Baseline
| Group | Normal metabolizers (n = 12) | Slow metabolizers (n = 12) |
| Race | ||
| African American | 8 | 9 |
| Caucasian | 4 | 3 |
| Age (y) | ||
| Mean ± SD | 48.7 ± 9.2 | 45.5 ± 11.6 |
| Range | 35–64 | 23–62 |
| Sex (n) | ||
| Male | 5 (42%) | 6 (50%) |
| Female | 7 (58%) | 6 (50%) |
| Cigarettes per day (n) | ||
| Mean ± SD | 16.9 ± 8.4 | 17.0 ± 3.4 |
| Range | 10–40 | 11–20 |
| FTND | ||
| Mean ± SD | 5.9 ± 2.2 | 5.4 ± 1.78 |
| Range | 2–9 | 2–8 |
| CO at intake (ppm) | ||
| Mean ± SD | 21.2 ± 5.8 | 25.0 ± 7.7 |
| Range | 12–29 | 12–35 |
| Plasma cotinine at intake (ng/mL) | ||
| Mean ± SD | 219.7 ± 64.1 | 323.9 ± 143.9 |
| Range | 119.8–329.2 | 154.1–604.5 |
| Plasma 3-hydroxycotinine at intake (ng/mL) | ||
| Mean ± SD | 104.6 ± 50.8 | 51.8 ± 27.8 |
| Range | 31.9–195.0 | 18.5–100.2 |
| Plasma NMR at intake | ||
| Mean ± SD | 0.467 ± 0.192 | 0.170 ± 0.059 |
| Range | 0.266–0.908 | 0.08–0.259 |
FTND = Fagerstrӧm Test for Nicotine Dependence.
No significant differences were present between normal and slow metabolizers (P = 0.67, 0.47, 0.7, 0.98, 0.62, and 0.18 for race, mean age, sex, cigarettes per day, FTND, and CO, respectively). Serum nicotine values are not included because time between last cigarette and sampling was not standardized.