TABLE 1

Patient Characteristics and Treatment

Patient no.Age (y)SexLocationWHO gradeBefore therapyOctreotide uptakeFractions/MBqKarnofsky performance statusResponse (RECIST)PFS/OS (mo)
Treatment category 1*
163MFalx bifrontalIIS, RTNA2/1,68880PD0/12
263FSkull base + parietalIS23/4,50090SD137+/137+
351FConvexity, multipleIIIS, RT, C34/8,43890PD4/22
456FSkull baseIS32/13,50090SD87+/87+
544MSkull baseIS, RT32/14,80090SD17/48+
646FSkull baseIS12/12,58080SD24+/24+
747FSkull baseIS32/12,95080SD72+/72+
867MConvexity, multipleIS, RT22/13,32060SD19/32
956FSkull baseIS22/11,840100SD14+/14+
Treatment category 2
1054FSkull baseII22/13,32090SD83+/83+
1164FSkull base + temporalNA32/14,80090SD68+/68+
1243FSkull baseNA22/13,69090SD56+/56+
1341FPineal regionI32/11,25050SD57/57
1471FSkull base + parietalNA32/12,21080SD18/18
1578FSkull baseIS12/13,32070SD14/16
  • * Treatment after subtotal surgery and other pretreatment/diffuse tumor growth.

  • Treatment due to severe medical comorbidity/refusal of surgical tumor resection.

  • Age = at initiation of 90Y-DOTATOC; RECIST = Response Evaluation Criteria In Solid Tumors; S = surgery; RT = radiotherapy; NA = not applicable; PD = progressive disease; SD = stable disease; + = ongoing; multiple = ≥3 tumor locations; C = chemotherapy.