TABLE 4

AD Diagnostic Accuracy Estimates for Clinical Evaluations

Subgroup
Identification	Description	PPV	NPV	PLR	NLR	TPR ± SE	TNR ± SE	CA ± SE	BA ± DA
3	AD	0.88						0.88 ± 0.07	0.50 ± 0.38
4	PPA-L (AD variant)		0.11					0.11 ± 0.07	0.50 ± 0.40
5	PPA-G		0.69					0.69 ± 0.12	0.50 ± 0.19
6	PPA-S		0.92					0.92 ± 0.07	0.50 ± 0.42
7	CBS		0.64					0.64 ± 0.13	0.50 ± 0.14
8	AD and PPA-L	0.88	0.11	0.92	1.12	0.55 ± 0.08	0.40 ± 0.22	0.53 ± 0.08	0.48 ± 0.06
9	PPA-G, PPA-S, and CBS		0.74					0.74 ± 0.07	0.50 ± 0.24
10	Entire cohort	0.88	0.57	5.90	0.63	0.41 ± 0.07	0.93 ± 0.04	0.65 ± 0.05	0.67 ± 0.02

PPV = positive predictive value; NPV = negative predictive value; PLR = positive likelihood ratio; NLR = negative likelihood ratio; TPR = rate of TP results; TNR = rate of TN results; CA = conventional accuracy; BA = balanced accuracy; DA = discordance of accuracies.