TABLE 3

Determinants of 18F-NaF Uptake in Ascending Aorta

DeterminantRegression coefficientβAdjusted R2P
NaFmax (kBq/mL)0.80<0.001
 Intercept (kBq/mL)3.54 (2.59 to 4.23)<0.001
 Blood activity (kBq/mL)0.94 (0.65 to 1.21)0.34<0.001
 MDRD-eGFR (mL/min/1.73 m2)−0.01 (−0.02 to −0.00)−0.110.020
 Injected dose (100 MBq)0.57 (0.18 to 1.23)0.190.008
 PET/CT system
  Discovery STE−2.16 (−2.56 to −1.76)−0.80<0.001
  Discovery VCT−2.14 (−2.55 to −1.74)−0.75<0.001
  Discovery RX−1.99 (−2.37 to −1.61)−0.79<0.001
TBRmax/mean0.69<0.001
 Intercept4.89 (4.03 to 5.68)<0.001
 Blood activity (kBq/mL)−1.27 (−1.75 to −0.90)−0.60<0.001
 MDRD-eGFR (mL/min/1.73 m2)−0.01 (−0.02 to −0.00)−0.120.034
 Injected dose (100 MBq)0.77 (0.39 to 1.34)0.330.001
 PET/CT system
  Discovery STE−1.67 (−2.03 to −1.33)−0.80<0001
  Discovery VCT−1.54 (−1.89 to −1.20)−0.70<0.001
  Discovery RX−1.55 (−1.86 to −1.24)−0.80<0.001
bsNaFmax (kBq/mL)0.74<0.001
 Intercept (kBq/mL)3.47 (2.63 to 4.10)<0.001
 MDRD-eGFR (mL/min/1.73 m2)−0.01 (−0.02 to −0.00)−0.130.019
 Injected dose (100 MBq)0.55 (0.24 to 1.13)0.210.006
 PET/CT system
  Discovery STE−2.15 (−2.52 to −1.78)−0.91<0.001
  Discovery VCT−2.12 (−2.49 to −1.78)−0.86<0.001
  Discovery RX−1.99 (−2.33 to −1.62)−0.91<0.001
  • β = standardized regression coefficient.

  • All models eliminated circulating time. In addition, blood activity was eliminated by model bsNaFmax. 95% confidence intervals are presented in parentheses.