Organ | Model | Normalized time integral (NTIM,i)* | Akaike-weighted normalized time integral (WNTIM,i) | Multimodel-averaged normalized time integral (MNTIi) |
Blood | ME | 0.597 | 0.000 | 1.127 |
MEC | 2.365 | 0.001 | ||
BE | 1.000 | 0.076 | ||
SE | 1.161 | 0.305 | ||
MSE | 1.326 | 0.306 | ||
SSE | 1.022 | 0.440 | ||
SMSE | 0.877 | 0.000 | ||
Kidneys | ME | 0.726 | 0.007 | 1.162 |
MEC | 1.019 | 0.429 | ||
BE | 1.000 | 0.123 | ||
SE | 0.966 | 0.040 | ||
MSE | 0.984 | 0.138 | ||
SSE | 1.168 | 0.010 | ||
SMSE | 1.619 | 0.415 | ||
Liver | ME | 0.907 | 0.000 | 1.328 |
MEC | 1.385 | 0.535 | ||
BE | 1.000 | 0.191 | ||
SE | 1.345 | 0.096 | ||
MSE | 1.364 | 0.380 | ||
SSE | 1.514 | 0.048 | ||
SMSE | 1.888 | 0.079 | ||
Bone marrow | ME | 1.000 | 0.363 | 1.540 |
MEC | 1.017 | 0.113 | ||
BE | 1.000 | 0.029 | ||
SE | 0.994 | 0.109 | ||
MSE | 1.003 | 0.109 | ||
SSE | 1.242 | 0.009 | ||
SMSE | 2.983 | 0.808 | ||
Lungs | ME | 0.631 | 0.000 | 0.999 |
MEC | 1.077 | 0.000 | ||
BE | 1.000 | 0.274 | ||
SE | 1.019 | 0.188 | ||
MSE | 1.065 | 0.025 | ||
SSE | 0.988 | 0.512 | ||
SMSE | 1.004 | 0.000 |
↵* NTIM,i = time integral for each (M-th) model and i-th organ/tissue, divided by time integral for BE model. WNTIM,i = NTIM,i multiplied by model’s Akaike weight. MNTIi is sum of WNTIM,i across all models and represents model-averaged estimate for time integral.