TABLE 2

TBF and PTF Values for Imatinib

Parameter BaselineDay 2Days 6–7
TBF, liver lesions0.34 ± 0.120.37 ± 0.120.36 ± 0.11
PTF, liver lesions0.61 ± 0.150.62 ± 0.160.71 ± 0.17*
TBF, all lesions0.44 ± 0.250.47 ± 0.270.47 ± 0.32
PTF, all lesions0.62 ± 0.120.62 ± 0.140.69 ± 0.13*
  • * P < 0.05, compared with baseline, Wilcoxon matched-pairs signed-ranks test.

  • Units are mL/min/mL of tissue for TBF and mL of perfused tissue/mL of total tissue for PTF.