TABLE 4

Multivariate Cox Regression with Respect to OS

Parameter	HR	Confidence interval	P
Clinical parameters
T stage	1.5	0.75–2.8	0.27
N stage	1.3	0.71–2.5	0.38
UICC stage	0.84	0.41–1.7	0.64
Smoker	1.7	1–2.8	0.045
PET parameters
MTV	1.8	1.1–2.9	0.019
TLG	1.5	0.94–2.4	0.086
TLG_SUR	1.6	0.95–2.7	0.083
$\text{[math]}$	1.6	0.94–2.8	0.084
SUV_max	1.6	0.99–2.7	0.056
SUR_max	2	1.2–3.6	0.012
$\text{[math]}$	1.9	1.1–3.2	0.019
SUR_mean	2.1	1.2–3.7	0.01
$\text{[math]}$	1.7	0.95–3.1	0.071

Each PET parameter was analyzed separately together with clinical parameters, which were significant prognostic factors (or exhibited a trend for significance) in univariate Cox regression. HRs and P values of clinical parameters were averaged over all analyses.