TABLE 2

Global and Regional DVRs

DVRWhole sampleLower tertileMiddle tertileUpper tertile
Number of participants55181918
Mean cDVR1.17 ± 0.26*0.93 ± 0.021.08 ± 0.09*1.49 ± 0.16*
Orbitofrontal cortex1.09 ± 0.270.86 ± 0.040.1 ± 0.141.40 ± 0.19
Prefrontal cortex1.11 ± 0.290.86 ± 0.041.02 ± 0.131.46 ± 0.19
Superior frontal gyrus1.20 ± 0.340.90 ± 0.041.08 ± 0.141.61 ± 0.22
Parietal lobe1.14 ± 0.240.92 ± 0.051.07 ± 0.081.42 ± 0.19
Medial temporal cortex1.01 ± 0.090.95 ± 0.071.01 ± 0.061.06 ± 0.11
Lateral temporal cortex1.13 ± 0.240.93 ± 0.031.05 ± 0.121.41 ± 0.19
Occipital cortex1.08 ± 0.130.99 ± 0.061.06 ± 0.071.19 ± 0.15
Anterior cingulate gyrus1.27 ± 0.340.97 ± 0.071.17 ± 0.181.67 ± 0.23
Posterior cingulate gyrus1.32 ± 0.351.02 ± 0.061.19 ± 0.11.76 ± 0.23
  • * Greater than DVR positivity cutoff of 1.062 for cDVR, indicating more than minimal Aβ.

  • All DVRs are significantly higher in upper tertile than lower tertile (P < 0.005).