TABLE 3

Comparison of Diagnostic Performance of 64Cu-DOTATATE and 111In-DTPA-OC

Parameter64Cu-DOTATATE111In-DTPA-octreotide
Sensitivity97% (91%–99%)*87% (79%–92%)*
Specificity100% (96%–100%)100% (96%–100%)
Accuracy97% (92%–99%)*88% (81%–93%)*
Positive predictive value†100% (97%–100%)100% (96%–100%)
Negative predictive value†80% (54%–94%)48% (30%–67%)

  • ↵* P = 0.017; 64Cu-DOTATATE vs. 111In-DTPA-OC (McNemar test for paired proportions).

  • ↵† At prevalence of disease of 89%.

  • Numbers in parentheses are 95% confidence intervals calculated using adjusted Wald method.